Informative missing genotypes: hopes for the craving revolution of genome-wide risk models

María M. Abad Grau, Ildefonso Camacho, Víctor Potenciano, Mohamed Abd Allah Makhlouf, Serafín Moral, Andrés Masegosa, Sergio Sánchez Torres, Eladio Garví, Christopher R. Gignoux, María I. García Sánchez, Guillermo Izquierdo Ayuso, Antonio Alcina and Fuencisla Matesanz

Download pdf

We have only submitted this work to Nature receving a negative answer from the Senior Editor without being sent to reviewers. We prefectly understand their answer. However we have decided not to submit this work to any other journal. Documents related to this work:

References

  1. Jager, P. D. et al. The role of the cd58 locus in multiple sclerosis. Proc. Natl. Acad. Sci. U. S. A. 106, 5264–69 (2008).
  2. Abad-Grau, M., Medina-Medina, N., Montes-Soldado, R., Matesanz, F. & Bafna, V. Sample reproducibility of genetic association using different multimarker tdts in genome-wide associa- tion studies: Characterization and a new approach. PLoS ONE 7, e29613 (2012).
  3. Abad-Grau, M. M., Medina-Medina, N., Masegosa, A. & Moral, S. Haplotype-based classifiers to predict individual susceptibility to complex diseases-an example for multiple sclerosis: 12 biostec-bioinformatics conference, Vilamoura, Algarve, Portugal, February 1-4, 2012. Proceed- ings. In BIOINFORMATICS 2012 - Proceedings of the International Conference on Bioinfor- matics Models, Methods and Algorithms, Vilamoura, Algarve, Portugal, 1 - 4 February, 2012., 360–366 (2012).
  4. ‘International Multiple Sclerosis Genetics Consortium’, D. H. et al. Risk alleles for multiple sclerosis identified by a genomewide study. New England Journal of Medicine 357, 851–62 (2007).
  5. Pino-Yanes, M. et al. Genome-wide association study and admixture mapping reveal new loci associated with total ige levels in latinos. Journal of Allergy and Clinical Immunology 135, 1502–1510 (2015).
  6. HapMap-Consortium, T. I. The international hapmap project. Nature 426, 789–796 (2003).